Lipids and Lipid Derivatives
Medchemexpress LLC Melatonin-d3 (N-Acetyl-5-methoxytryptamine-d3) | 90735-69-6 | 99.1% | C13H13D3N2O2 | 5 MG
Melatonin-d3 is the deuterium labeled version of Melatonin. Melatonin is a hormone that activates melatonin receptors, playing a role in sleep and possessing antioxidative and anti-inflammatory properties. It is also identified as a selective ATF-6 inhibitor, inducing apoptosis in human hepatoma cells by downregulating COX-2, and can reduce palmitic acid-induced apoptosis in mouse granulosa cells by alleviating endoplasmic reticulum stress.
- Used as a tracer
- Serves as an internal standard for quantitative analysis
- Stable heavy isotopes for drug development quantitation
- Deuteration can influence pharmacokinetic and metabolic profiles
- Powder storage: -20°C for 3 years, 4°C for 2 years
- Solvent storage: -80°C for 6 months, -20°C for 1 month
Medchemexpress LLC HY-32348 5mg Medchemexpress, Doxercalciferol CAS:54573-75-0 Purity:>98%
Medchemexpress, HY-32348 5mg Doxercalciferol CAS:54573-75-0 Doxercalciferol is a Vitamin D2 analog, acts as an activator of Vitamin D receptor, and prevent renal disease. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
Medchemexpress LLC Tacalcitol (1α,24R-dihydroxyvitamin D3) | 57333-96-7 | MFCD00866623 | 99.7% | 416.64 | C27H44O3 | 10 MG
Tacalcitol is a synthetic vitamin D3 analogue supplied as a solid research chemical for studies of bone growth, calcium regulation, inflammation, cancer biology, and dermatological research. The material is a white to off-white powder with high purity and is suitable for in vitro applications when dissolved in appropriate solvents.
- Synthetic vitamin D3 analogue for research applications.
- High purity (99.7%).
- White to off-white solid powder.
- Available in small pack sizes, including 10 mg vials.
- Soluble in DMSO at ≥100 mg/mL for in vitro use.
- Store at 4°C, protect from light, and keep under inert atmosphere for long-term stability.
Medchemexpress LLC Cyclin D2/CCND2 Antibody (YA789) | Predicted band size: 33 kDa; Observed band size: 38 kDa | 100 UL
The Cyclin D2/CCND2 Antibody (YA789) is a Mouse-derived, non-conjugated IgG2b monoclonal antibody designed to target Cyclin D2/CCND2. It is suitable for use in Western Blot (WB) applications.
- Mouse-derived
- Monoclonal antibody
- Reacts with human samples
- Supplied in 1x PBS, 50% glycerol, 0.5% BSA, and 0.02% sodium azide
- Recommended storage at -20°C for up to one year
- Affinity purified
- Non-conjugated
- Isotype IgG2b
Medchemexpress LLC Cyclin D2/CCND2 antibody (YA789) | Affinity purified | Predicted band size: 33 kDa; Observed band size: 38 kDa | 10 UL
Cyclin D2/CCND2 antibody (YA789) is a mouse-derived, non-conjugated IgG2b monoclonal antibody targeting Cyclin D2/CCND2. It is formulated in 1x PBS (pH 7.3), 50% glycerol, and 0.5% BSA, containing 0.02% sodium azide as a preservative. This antibody is intended for research use only and reacts with human species.
- Host: Mouse
- Clonality: Monoclonal
- Isotype: IgG2b
- Species reactivity: Human
- Purity: Affinity purified
- Applications: Western Blot (WB)
- Immunogen: Synthetic peptide corresponding to human Cyclin D2
- Storage: Store at -20°C for 1 year, avoid repeated freeze/thaw cycles
Medchemexpress LLC Ofloxacin-d3 | 1173147-91-5 | 99.8% | 1 MG
Ofloxacin-d3 is a deuterium-labeled form of Ofloxacin designed for research applications. It serves as a tracer and an internal standard, facilitating quantitative analysis in methods like NMR, GC-MS, or LC-MS. This compound leverages stable heavy isotopes, which are incorporated into drug molecules to aid quantitation during drug development and may influence pharmacokinetic and metabolic profiles.
- Deuterium labeled Ofloxacin.
- Intended for research use only.
- Functions as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes into drug molecules.
- Potential to affect pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Menadione-d3 | 5172-16-7 | 99.1% | 25 MG
Menadione-d3 is the deuterium labeled Menadione. Menadione, a synthetic naphthoquinone, can be converted to active vitamin K2 in vivo. It is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration has the potential to affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Pefloxacin-d3 | 2733455-58-6 | 99.4% | 5 MG
Pefloxacin-d3 (Pefloxacinium-d3) is a deuterium-labeled version of the broad-spectrum antibiotic Pefloxacin. It blocks DNA replication by inhibiting DNA gyrase and also inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. This compound demonstrates antibacterial activity against various bacteria such as *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*.
- Deuterium labeled version of Pefloxacin
- Broad-spectrum antibiotic
- Inhibits DNA gyrase, blocking DNA replication
- Inhibits DNA relaxation catalyzed by topoisomerase I
- Exhibits antibacterial activity against *Escherichia coli*, *Pseudomonas aeruginosa*, and *Bacteroides fragilis*
- Shows anti-*Plasmodium yoelii* infection activity
- Can be used as a tracer
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Vitamin D3 | 67-97-0 | C27H44O | 100 MG
Vitamin D3 (Cholecalciferol; Colecalciferol) is a naturally occurring form of vitamin D. It induces cell differentiation and prevents the proliferation of cancer cells. This product is an analytical standard and is intended for research and analytical applications.
- Used as a reference standard in assays.
- Utilized in qualitative, quantitative, and methodological research experiments in HPLC, GC, and MS.
- Induces cell differentiation.
- Prevents proliferation of cancer cells.
Cayman Chemical 25-hydroxy VItamIn D3 5mg
An intermediate in the pathway leading to the production of 1,25-dihydroxy vitamin D3; plasma or serum levels are commonly used as an indicator of an individual’s vitamin D status
Medchemexpress LLC 3-pyridin-3-ylpropyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)pyrrolidine-2-carboxylate | 186452-09-5 | MFCD00953146 | 99.8% | 360.45 g/mol | C20H28N2O4 | 10MG
GPI-1046 is a non-immunosuppressive immunophilin ligand used in research for its neuroprotective effects. It has been reported to upregulate glutamate transporter 1 (GLT1), reduce ethanol intake, and attenuate HIV-associated sensory neuropathy by modulating store-operated calcium entry. The compound is provided as a high-purity liquid (formula C20H28N2O4, MW ~360.45 g/mol).
- Non-immunosuppressive immunophilin ligand
- Reported neuroprotective activity
- Upregulates glutamate transporter 1 (GLT1)
- Attenuates HIV-associated sensory neuropathy via store-operated calcium entry modulation
- High purity (≈99.8%)
- Liquid appearance: colorless to light yellow
- Chemical formula C20H28N2O4; molecular weight ~360.45 g/mol
- Storage: 4°C, protect from light; in solvent: -80°C (6 months), -20°C (1 month)
TARGETMOL CHEMICALS INC DOXERCALCIFEROL 10MG
Also available in 1 mg 2 mg 5 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Doxercalciferol (TSA 840) is a synthetic vitamin D2 analog suppressing parathyroid synthesis and secretion used to treat secondary hyperparathyroidism and metabolic bone disease. purity: 99%
Medchemexpress LLC Calcipotriol Impurity C | 113082-99-8 | 99.1% | C27H40O3 | 5 MG
Calcipotriol Impurity C is an impurity of Calcipotriol, which functions as a ligand for VDR-like receptors. This product is intended for research use only.
- Functions as a ligand for VDR-like receptors
- Target is VDR (Vitamin D Receptor)
- Soluble in DMSO
- Soluble in 10% DMSO >> 90% (20% SBE-β-CD in saline)
- Soluble in 10% DMSO >> 90% corn oil
- Store at 4°C, protected from light, under nitrogen
- Store in solvent at -80°C for 6 months or -20°C for 1 month, protected from light, under nitrogen
Medchemexpress LLC 5,6-trans-Vitamin D2 | 51744-66-2 | 97.0% | C28H44O | 100 MG
5,6-trans-Vitamin D2 is an isomer of Vitamin D2. It is supplied as an off-white to light yellow solid with a molecular weight of 396.65. This product is for research use only and not intended for patient use.
- Isomer of vitamin D2
- For research use only
- Molecular weight of 396.65
- Appears as an off-white to light yellow solid
- Soluble in DMSO (25 mg/mL)
- In vivo dissolution protocols available